生体医工学研究室(塚田研究室)

論文・研究発表

国際原著論文Yamada H., Kawai R., Niwa R., Tsukada K., Two-Dimensional array sinusoidal waves conductor for biometric measurements, IEEE Open Journal of Engineering in Medicine and Biology , in press.
https://doi.org/10.1109/OJEMB.2024.3374975
Sugiyama S., Sudo H., Tsukada K., Three-dimensional microfluidic cell culture device that generates chemical and oxygen gradients, Japanese Journal of Applied Physics, 63, 03SP48, 2024.
https://doi.org/10.35848/1347-4065/ad23a8
Shirai H., Tsukada K., Understanding bacterial infiltration of the pancreas through a deformable pancreatic duct, Journal of Biomechanics, 162, 111883, 2024.
https://doi.org/10.1038/s41598-022-05554-8
Shirai H., Ito C., Tsukada K., pH-taxis drives aerobic bacteria in duodenum to migrate into the pancreas with tumors, Scientific Reports, 12, 1783, 2022.
https://doi.org/10.1038/s41598-022-05554-8
Hosoda M., Oida D., Ito K., Takae S, Suzuki N., Tsukada K., Ex vivo sensing of primordial follicles in ovarian tissues by spectral-domain optical coherence tomography, Proc. SPIE 12036, Medical Imaging 2022: Biomedical Applications in Molecular, Structural, and Functional Imaging, 120360J, 2022.
https://doi.org/10.1117/12.2607462
Saito K., Motani Y., Takae S., Suzuki N., Tsukada K., Convolutional neural network-based automatic detection of follicle cells in ovarian tissue using optical coherence tomography, Biomedical Physics & Engineering Express, 6, 065026, 2020.
https://doi.org/10.1088/2057-1976/abc3d4
Katayama Y., Fujioka Y., Tsukada K., Development of a patch-type flexible oxygen partial pressure sensor, IEEE Journal of Translational Engineering in Health & Medicine, 8, 1400607, 2020.
https://doi.org/10.1109/JTEHM.2020.3005477
Shirai H., Tsukada K., Drug delivery in tumors is enhanced by bacterial proteolytic activity in a size, pharmacokinetic, and binding affinity dependent manner -A mechanistic understanding, Journal of Controlled Release, 321, 348-362, 2020.
https://doi.org/10.1016/j.jconrel.2020.02.024
Katagiri W., Lee G.H., Tanushi A., Tsukada K., Choi H.S., Kashiwagi S., High-throughput single-cell live imaging of photobiomodulation with multispectral near-infrared lasers in cultured T cells, Journal of Biomedical Optics, 25(3), 036003, 2020.
https://doi.org/10.1117/1.JBO.25.3.036003
Kaminota N. Ogawa E., Kumagai H., Tsukada K., Arai T., Respiration and heat shock protein after short-term heating/stretch-fixing on smooth muscle cells, Cardiovascular Engineering and Technology, 11(3), 308-315, 2020.
https://doi.org/10.1007/s13239-020-00458-y
Shibusawa K., Hase T., Tsukada K., Increasing surface-enhanced Raman scattering density using gold-coated magnetic nanoparticles controlled via a magnetic field for sensitive and efficient biomarker detection, AIP Advances, 9, 065316, 2019.
https://doi.org/10.1063/1.5102083
Katagiri W., Lee J.H., Tetrault M.A., Kang H., Jeong S., Evans C.L., Yokomizo S., Santos S., Jones C., Hu S., Fakhri G.E., Tsukada K., Choi H.S., Kashiwagi S., Real-time imaging of vaccine biodistribution using zwitterionic NIR nanoparticles, Advanced Healthcare Materials, e1900035, 2019.
https://doi.org/10.1002/adhm.201900035
Yabuki Y., Iwamoto Y. and Tsukada K., Micro/nano particle-based oxygen sensing film for monitoring respiration of cells cultured in a microfluidic device, Japanese Journal of Applied Physics, 58, SDDK03, 2019.
https://doi.org/10.7567/1347-4065/ab049b
Kimizuka Y., Katagiri W., Locascio J.J., Shigeta A., Sasaki Y., Shibata M., Morse K., Sirbulescu R.F., Miyatake M., Reeves P., Suematsu M., Gelfand J., Brauns T., Poznansky M.C., Tsukada K., Kashiwagi S., Brief exposure of skin to near-infrared laser modulates mast cell function and augments the immune response, The Journal of Immunology, 201(12), 3587-3603, 2018.
Takae S., Tsukada K., Maeda I., Sato Y., Okamoto N., Kondo H., Motani Y., Suzuki N., Preliminary clinical study of optical coherence tomography intended for investigating effective ovarian tissue transplantation, Journal of Assisted Reproduction and Genetics, 35(4), 627-636, 2018.
Hase T., Ishigaki S., Shibusawa K., Hamanaka S., Yabuki Y., Tamano Y., Tsukada K., Immobilized monolayer nanoparticles in a microfluidic device for surface enhanced Raman scattering measurement, Advanced Biomedical Engineering, 6, 122-128, 2017.
Park J.Y., Kyung K.H., Tsukada K., Kim S.H., Shiratori S., Biodegradable polycaprolactone nanofibres with β-chitosan and calcium carbonate produce a hemostatic effect, Polymer, 123, 194-202, 2017.
Morse K., Kimizuka Y., Chan M.P.K., Shibata M., Shimaoka Y., Takeuchi S., Forbes B., Nirschl C.J., Li B., Zeng Y., Bronson R., Katagiri W., Shigeta A., Sirbulescu R.F., Chen H., Tan R.Y.Y., Tsukada K., Brauns T., Gelfand J.A., Sluder A., Locascio J.J., Poznansky M.C., Anandasabapathy N., Kashiwagi S., Near-infrared 1064 nm laser modulates migratory dendritic cells to adjuvant the immune response to intradermal influenza vaccine, The Journal of Immunology, 199(4), 1319-1332, 2017.
Kimizuka Y., Callahan J.J., Huang Z., Morse K., Katagiri W., Shigeta A., Bronson R., Takeuchi S., Shimaoka Y., Chan M.P.K., Zeng Y., Li B., Chen H., Tan R.Y.Y., Dwyer C., Mulley T., Leblanc P., Goudie C., Gelfand J., Tsukada K.., Brauns T., Poznansky M.C., Bean D., Kashiwagi S., Semiconductor diode laser device adjuvanting intradermal vaccine, Vaccine, 35, 2404-12, 2017.
Takae S., Tsukada K., Sato Y., Okamoto N., Kawahara T., Suzuki N., Accuracy and safety verification of ovarian reserve assessment technique for ovarian tissue transplantation using optical coherence tomography in mice ovary, Scientific Reports, 7, 43550 (8 pages), 2017.
Oda K., Iwamoto Y., Tsukada K., Simultaneous mapping of unevenly distributed tissue hypoxia and vessel permeability in tumor microenvironment, Biomedical Physics & Engineering Express, 2, 065017, 2016.
Ishikawa M., Kajimura M., Morikawa T., Tsukada K., Tsuji T., Kusaka G., Tanaka Y., Suematsu M., Cortical microcirculatory disturbance in the super acute phase of subarachnoid hemorrhage - In vivo analysis using two-photon laser scanning microscopy, Journal of the Neurological Sciences, 368, 326-33, 2016.
Nishioka S., Tenjimbayashi M., Manabe K., Matsubayashi T., Suwabe K., Tsukada K., Shiratori S., Facile design of plant-oil-infused fine surface asperity for transparent blood-repelling endoscope lens, RSC Advances, 6, 47579-87, 2016.
Ishikawa M., Kajimura M., Morikawa T., Tsukada K., Tsuji T., Kusaka G., Tanaka Y., Suematsu M., Leukocyte plugging and cortical capillary flow after subarachnoid hemorrhage, Acta Neurochirurgica, 158(6), 1057-67, 2016.
Sato A., Kadokura K., Uchida H., Tsukada K., An in vitro hepatic zonation model with a continuous oxygen gradient in a microdevice, Biochemical and Biophysical Research Communications, 453, 767-71, 2014.
Yamada R., Tabuchi S., Tsukada K., Optical scanning of tissue oxygen tension and hypoxia imaging in solid tumors, Advanced Biomedical Engineering, 3, 65-71, 2014.
Takada Y., Otsuka R., Tsukada K., A carbon monoxide sensing film based on hemoglobin allostery, Journal of Biomedical Science and Engineering, 7, 173-180, 2014.
Kashiwagi S., Yuan J., Forbes B., Hibert M.L., Lee E.L., Whicher L., Goudie C., Yang Y., Chen T., Edelblute B., Collette B., Edington L., Trussler J., Nezivar J., Leblanc P., Bronson R., Tsukada K., Suematsu M., Dover J., Brauns T., Gelfand J., Poznansky M.C., Near-infrared laser adjuvant for influenza vaccine, PLoS ONE, 8(12), e82899, 2013.
Uchida H., Sato A., Miyayama A., Tsukada K., Generation of an oxygen gradient in a microfluidic device and cellular analysis in hypoxia, Advanced Biomedical Engineering, 2, 143-149, 2013.
Tsukada K., Tajima T., Hori S., Matsuura T., Johnson R.S., Goda N. and Suematsu M., Hypoxia-inducible factor-1 is a determinant of lobular structure and oxygen consumption in the liver, Microcirculation, 20(5), 385-93, 2013.
Tsukada K. and Suematsu M., Visualization and analysis of blood flow and oxygen consumption in hepatic microcirculation: application to an acute hepatitis model, Journal of Visualized Experiments, 66, e3996 (5 pages), 2012.
Shiwa T., Uchida H. and Tsukada K., Co-culture microdevice with oxygen gradient for tumor microenvironment model and metastasis imaging, Am. J. Biomed. Eng., 2(4), 175-180, 2012.
Handa K., Ohmura M., Nishime C., Hishiki T., Nagahata Y., Kawai K., Suemizu H., Nakamura M., Wakui M., Kitagawa Y., Suematsu M. and Tsukada K., Phosphorescence assisted microvascular O2 measurements reveal alterations of oxygen demand in human metastatic colon cancer in the liver of superimmunodeficient NOG mice, Advances in Experimental Medicine and Biology, 662, 423-9, 2010.
Akatsu T., Tsukada K., Hishiki T., Suganuma K., Tanabe M., Shimazu M., Kitagawa Y., Yachie-Kinoshita A. and Suematsu M., T-state stabilization of hemoglobin by nitric oxide to form a-nitrosyl heme causes constitutive release of ATP from human erythrocytes, Advances in Experimental Medicine and Biology, 662, 109-14, 2010.
Kondo K., Sugioka T., Tsukada K., Aizawa M., Takizawa M., Shimizu K., Morimoto M., Suematsu M. and Goda N., Fenofibrate, a peroxisome proliferator-activated receptor _ agonist, improves hepatic microcirculatory patency and oxygen availability in a high-fat-diet-induced fatty liver in mice, Advances in Experimental Medicine and Biology, 662, 77-82, 2010.
Kashiwagi S., Tsukada K., Xu L., Miyazaki J., Kozin S.V., Tyrrell J.A., Sessa W.C., Gerweck L.E., Jain R.K., Fukumura D., Perivascular nitric oxide gradients normalize tumor vasculature, Nature Medicine, 14(3), 255-7, 2008.
Kinoshita A., Tsukada K., Soga T., Hishiki T., Ueno Y., Nakayama Y., Tomita M., Suematsu M., Roles of hemoglobin allostery in hypoxia-induced metabolic alterations in erythrocytes: simulation and its verification by metabolome analysis, Journal of Biological Chemistry, 282(14), 10731-41, 2007.
Tsukada K.*, Suganuma K.*, Kashiba M., Tsuneshige A., Goda N., Kitajima M., Yonetani T., Suematsu M. (*equally contributed): Erythrocytes with T-state-stabilized hemoglobin as a therapeutic tool for post-ischemic liver dysfunction, Antioxidants & Redox Signaling, 8, 1847-55, 2006.
Suematsu M., Tsukada K., Tajima T., Yamamoto T., Ochiai D., Watanabe H., Yoshimura Y., Goda N.: Carbon monoxide as a guardian against hepatobiliary dysfunction, Alcoholism, clinical and experimental research, 29 (11), 134S-139S, 2005.
Tsukada K., Sekizuka E., Oshio C., Tsujioka K., Minamitani H.: Red blood cell velocity and oxygen tension measurement in cerebral microvessels by double-wavelength photoexcitation, Journal of Applied Physiology, 96(4), 1561-8, 2004.
Tsukada K., Sakai S., Hase K., Minamitani H.: Development of catheter-type optical oxygen sensor and applications to bioinstrumentation, Biosensors and Bioelectronics, 18(12), pp 1439-1445, 2003.
Minamitani H., Tsukada K., Sekizuka E. and Oshio C.: Imaging and functional analysis of blood flow in organic microcirculation, Journal of Pharmacological Science, 93(3), pp.227-33, 2003.
Ishikawa M., Sekizuka E., Oshio C., Sato S., Yamaguchi N., Terao S., Tsukada K., Minamitani H. and Kawase T.: Platelet adhesion and arteriolar dilation during photothrombosis -observation with rat closed cranial and spinal windows-, Journal of Neurological Science, 194(1), pp. 59-69, 2002.
Tsukada K., Sekizuka E., Oshio C., Minamitani H.: Direct measurement of erythrocyte deformability in diabetes mellitus with transparent microchannel capillary model and high-speed video camera system, Microvascular Research, 61(3), pp 231-9, 2001.
Tsukada K., Minamitani H., Sekizuka E., Oshio C.: Image correlation method for measuring blood flow velocity in microcirculation: correlation 'window' simulation and in vivo image analysis, Physiological Measurement, 21(4), pp 459-71, 2000.
国際会議発表Sugiyama S., Sudo H., Tsukada K., Development of a microfluidic device for three-dimensional cell culture under chemical gradients, 36th International Microprocesses and Nanotechnology Conference (MNC 2023), 2023-11 (Sapporo, Japan).
Kanaya M., Saito K., Ito K., Takae S., Suzuki N., Tsukada K., Machine learned automatic detection of follicles in ovarian tissues visualized by optical coherence tomography, 2023 Annual Meeting of BMES, 2023-10 (Seattle, USA).
Ito K., Kanaya M., Hosoda M., Takae S., Suzuki N., Tsukada K., Swept source optical coherence microscopy for imaging primordial follicles deep in ovarian tissues, 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2023-07 (Sydney).
Yamada H., Kawai R., Tsukada K., Electrical properties of a flexible conductor with two dimensional sinusoidal waves, 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2023-07 (Sydney).
Ito K., Hosoda M., Takae S., Suzuki N., Tsukada K., Supercontinuum Based Near Infrared Optical Coherence Tomography for Ovarian Follicle Detection, 2022 Annual Meeting of BMES, 2022-10 (San Antonio, USA).
Sugiyama S., Ito C., Tsukada K., Quantitative Analysis of In Vitro Angiogenesis Using Region Based Convolutional Neural Networks, 2022 Annual Meeting of BMES, 2022-10 (San Antonio, USA).
Hosoda M., Oida D., Ito K., Takae S., Suzuki N., Tsukada K., Ex vivo sensing of primordial follicles in ovarian tissues by spectral-domain optical coherence tomography, SPIE Medical Imaging, 2022-3 (San Diego, USA).
Katayama Y., Fujioka Y., Tsukada K., Development of a patch-type flexible oxygen partial pressure sensor, IEEE Special Topic Conference on Healthcare Innovations and Point of Care Technologies (HI-POCT), 2019-11 (Bethesda, USA).
Roth J., Iwamoto Y., Tsukada K., Single and multi-photon excitation using a supercontinuum laser for oxygen metabolism imaging, 2019 Annual Meeting of BMES, 2019-10 (Philadelphia, USA).
Shirai H., Tsukada K., Mathematical modeling of simultaneous penetration of liposomal doxorubicin and Clostridium in tumors ­– Implications for combination therapy, 2019 Annual Meeting of BMES, 2019-10 (Philadelphia, USA).
Saito K., Motani Y., Takae S., Suzuki N. and Tsukada K., Development of methods to visualize and quantify follicle cells in ovarian tissue by optical coherence tomography, 41st International Engineering in Medicine and Biology Conference (IEEE EMBC 2019), 2019-7 (Berlin, Germany).
Shibusawa K., Hase T. and Tsukada K., Magnetic field-controllable cluster nanoparticles for surface enhanced Raman scattering, 31st International Microprocesses and Nanotechnology Conference (MNC 2018), 2018-11 (Sapporo, Japan).
Yabuki Y., Yokoyama J. and Tsukada K., Micro/nano particle-based oxygen sensing film for monitoring respiration of cells cultured in a microfluidic device, 31st International Microprocesses and Nanotechnology Conference (MNC 2018), 2018-11 (Sapporo, Japan).
Fujioka Y., Katayama Y., Tsukada K., Development of flexible oxygen sensor for direct measurement of vital oxygen partial pressure, IEEE Life Sciences Conference (LSC) 2018, 2018-10 (Montreal, Canada).
Takae S., Tsukada K., Sato Y., Okamoto N., Nishijima C., Suzuki Y., Yoshioka N., Sugishita Y., Horage U., Kondo H., Kawamura K., Suzuki N., Quantification and localization of primordial follicle using optical coherence tomography intended for investigating effective ovarian tissue transplantation, 8th Congress of the Asia Pacific Initiative on Reproduction, 2018-4 (Taipei, Taiwan).
Iwamoto Y., Oda K., Tsukada K., Quantification and imaging of vascular permeability and partial pressure of oxygen in vivo, 2017 Annual Meeting of BMES, 2017-10 (Phoenix, USA).
Katagiri W., Tsukada K., Three-dimensional in vivo analysis of histology for low-level laser therapy, 2017 Annual Meeting of BMES, 2017-10 (Phoenix, USA).
Takae S., Tsukada K., Okamoto N., Sato Y., Kawahara T., Suzuki N., Verification of accuracy & safety for ovarian reserve assessment with optical coherence tomography using mouse ovary, The ASRM Annual Meeting 2016, 2016-10 (Salt Lake City, USA).
Park J., Kyung K., Kim S., Tsukada K., Shiratori S., Biodegradable nanofiber with beta-chitosan and calcium carbonate for hemostatic effect, Biomaterials International 2016, 2016-10 (Kenting, Taiwan).
Boudehent B., Kadokura K. and Tsukada K., Quantitative analysis of HUVEC tube formation in culture under an oxygen gradient, 2016 Annual Meeting of BMES, 2016-10 (Minneapolis, USA).
Kadokura K., Sato A., Boudehent B. and Tsukada K., A cell culture device with continuous oxygen gradient for microcirculation research in vitro, 2016 Annual Meeting of BMES, 2016-10 (Minneapolis, USA).
Shiratori S., Nishioka S., Sasaki K., Tenjimbayashi M. and Tsukada K., Durable blood-repelling surface coating for medical application, Biomaterials International 2016, 2016-8 (Kenting, Taiwan).
Nishioka S., Tenjinbayashi M., Tsukada K. and Shiratori S., Anti-biofouling surface with plant oil infused porous structure for laparoscope lenses, The 2015 International Chemical Congress of Pacific Basin Societies, 2015-12 (Hawaii, USA).
Kadokura K., Sato A., Okazaki Y. and Tsukada K., A cell culture microdevice with a continuous oxygen gradient for microvascular research in vitro, 10th World Congress for Microcirculation 2015-9, (Kyoto, Japan).
Oda K., and Tsukada K., Quantification and imaging of regional vascular permeability and partial pressure oxygen, 10th World Congress for Microcirculation, 2015-9 (Kyoto, Japan).
Kadokura K., Sato A., Uchida H. and Tsukada K., Angiogenesis imaging in a cell culture microfluidic device mimicking the tumor microenvironment, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2015-8 (Milano, Italy).
Hase T., Tamano Y. and Tsukada K., Direct measurement of glycolytic metabolites with nanoparticle-based surface-enhanced Raman scattering, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2015-8 (Milano, Italy).
Ando Y., Yanagisawa Y. and Tsukada K., An organic light-emitting diode for oxygen sensing based on phosphorescence lifetime, 2014 Annual Meeting of BMES, 2014-10 (San Antonio, USA).
Morse K., Yuan J., Forbes B.M., Hibert M.L., Lee E.L.Q., Tan R.Y.Y., Whicher L., Goudie C., Yang Y., Chen T., Edelblute B., Collette B., Edington L., Trussler J., Nezivar J., Leblanc P., Bronson R., Tsukada K., Suematsu M., Dover J., Brauns t., Gelfand J., Poznansky M.C., Kashiwagi S., Near-Infrared Lasers to Adjuvant Vaccines, Infectious Disease World Summit, 2014-7 (Boston, USA).
Tsukada K., Laser-assisted hypoxia imaging for tumor biology, 37th Naito Conference, 2014-7 (Niseko, Japan).
Sato A., Uchida H., Miyayama A. and Tsukada K., Development of a microfluidic device forming oxygen gradient for cellular experiments, 26th International Microprocesses and Nanotechnology Conference (MNC 2013), 2013-11 (Sapporo, Japan).
Tomita K. and Tsukada K., An identification system for unstained cells using Mie scattering, 2013 Annual Meeting of BMES, 2013-9 (Seattle, USA).
Miyayama A., Uchida H., Sato A. and Tsukada K., Development of oxygen-sensing films and their application in biometry, 2013 Annual Meeting of BMES, 2013-9 (Seattle, USA).
Tsukada K., Generation of oxygen gradients in microfabricated devices for hypoxia research in vitro, Collaborative Conference on Materials Research (CCMR) 2013, 2013-6 (Jeju, Korea).
Osaki H., Tamano Y. and Tsukada K., Fluorescence reduction in time-resolved Raman spectroscopy for the detection of circulating tumor cells, 2012 Annual Meeting of BMES, 2012-10 (Atlanta, USA).
Yoshida R., Yanagisawa Y. and Tsukada K., Development of a phosphorescence-based oxygen sensor using organic electroluminescence, 2012 Annual Meeting of BMES, 2012-10 (Atlanta, USA).
Uchida H., Shiwa T., Sato A. and Tsukada K., Development of a microfluidic device forming oxygen gradient for cell culture, 2012 Annual Meeting of BMES, 2012-10 (Atlanta, USA).
Yamada R., Horinouchi H. and Tsukada K., Spatiotemporal measurement of tumor oxygenation reveals repeat hypoxic phenomenon in mice, 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2011-9 (Boston, USA).
Sasaki N., Horinouchi H., Ushiyama A., Tsukada K. and Minamitani H., Oxygen diffusion constant and oxygen consumption in arteriolar wall in vivo, International Society for Oxygen Transport to Tissues, 2009-7 (Cleveland, USA).
Tsukada K., Conner D., Lin Q., Kucherlapati R., Jain RK and Fukumura D., Blockade of inducible nitric oxide synthase normalizes murine breast cancer vessels, 100th American Association for Cancer Research, 2009-4 (Denver, USA).
Handa K., Ohmura M., Nishime C., Hishiki T., Nagahata Y., Kawai K., Suemizu H., Nakamura M., Wakui M., Kitagawa Y., Suematsu M. and Tsukada K., Phosphorescence assisted microvascular O2 measurements reveal alterations of oxygen demand in human metastatic colon cancer in the liver of superimmunodeficient NOG mice, International Society for Oxygen Transport to Tissues 2008, 2008 (Sapporo, Japan).
Akatsu T., Tsukada K., Hishiki T., Suganuma K., Tanabe M., Shimazu M., Kitagawa Y., Yachie-Kinoshita A. and Suematsu M., T-state stabilization of hemoglobin by nitric oxide to form a-nitrosyl heme causes constitutive release of ATP from human erythrocytes, International Society for Oxygen Transport to Tissues 2008, 2008 (Sapporo, Japan).
Kondo K., Sugioka T., Tsukada K., Aizawa M., Takizawa M., Morimoto M., Suematsu M., Goda N.: Fenofibrate, a peroxisome proliferator-activated receptor a agonist, improves hepatic microcirculatory patency and oxygen availability in a high-fat diet-induced fatty liver in mice, International Society for Oxygen Transport to Tissues 2008, 2008 (Sapporo, Japan).
Kinoshita A., Tsukada K., Soga T., Hishiki T., Tomita M. and Suematsu M.: Phosphofructokinase is critical for hypoxia-induced activation of glycolysis in human erythrocytes: Prediction by simulation and verification by metabolome analysis, 8th World Congress for Microcirculation, 2007-8 (Milwaukee, USA).
Tsukada K., Tajima T., Kawamura T., Goda N., Johnson R., Suematsu M.: Hypoxia inducible factor-1 modulates oxygen consumption in hepatocytes, American Society for Cell Biology 46th Annual Meeting, 2006-12 (San Diego, USA).
Tsukada K., Tajima T., Kawamura T., Goda N., Johnson R., Suematsu M.: Increased oxygen consumption in hepatocyte-specific HIF-1α-targeted mice, 24th European Conference on Microcirculation, 2006-8 (Amsterdam).
Tsukada K., Tajima T., Goda N., Johnson R., Suematsu M.: HIF-1 as a modulator of oxygen consumption in hepatocytes, 20th international congress of biochemistry and molecular biology, 2006-6 (Kyoto).
Tsukada K., Tajima T., Goda N., Soga T., Johnson R., Suematsu M.: Hepatocyte-specific gene targeting of hypoxia-inducible factor-1 blunts hepatic regeneration and remodeling of oxygen metabolism after partial hepatectomy, 4th HO conference, 2005-10 (Boston).
Akatsu T., Kajimura M., Tsukada K., Mizuno R., Ohhashi T., Suematsu M.: Involvement of erythrocyte in hypoxic vasodialtion: role of ATP from the cell. The 30th Annual Meeting of The Japanese Society for Microcirculation and 6th Asian Congress for Microcirculation, 2005-2 (Tokyo).
Tsukada K., Suganuma K., Yonetani T., Suematsu M.: T-state stabilization of hemoglobin allostery: A potential therapeutic stratagem for post-ischemic organ microvascular damages, 6th Asian Congress for Microcirculation, 2005-2 (Tokyo).
Arai T., Tsukada K., Sekizuka E., Oshio C., Terao S., Hase K., Minamitani H., Effect of hemodilution on oxygen supply to brain cortical arterioles, 25th Annual International coference of the IEEE-EMBS and Annual Fall Meeting of the BMES, 2003-9 (Cancun).
Hase K., Sakai S., Tsukada K., Sekizuka E., Oshio C., Minamitani H., Continous measurement of blood oxygen pressure using a fiber optic sensor based on phosphorescence quenching, 24th Annual International coference of the IEEE-EMBS and Annual Fall Meeting of the BMES, 2002-10 (Houston).
Minamitani H., Kawamura T., Sekizuka E., Tsukada K. and Oshio C., Viscoelasticity of diabetic erythrocytes measured by microscopic flow imager and atomic force microscope, The 7th world congress for microcirculation, 2001-8 (Sydney).
Tsukada K., Hase K., Sekizuka E., Oshio C. and Minamitani H., Blood flow imaging and oxygen measurement by photoexcitation during haemorragic shock, The 7th world congress for microcirculation, 2001-8 (Sydney)
Minamitani H., Tsukada K., Kawamura T., Sekizuka E. and Oshio C., Analysis of elasticity and deformability of erythrocytes using micro-channel flow system and atomic force microscope, 1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine & Biology, 2000-10 (Lyon).
Tsukada K., Hase K., Sekizuka E., Oshio C and Minamitani H., Simultaneous measurement of blood flow distribution and oxygen tension by photo-excitation in organ microcirculation, 1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine & Biology, 2000-10 (Lyon).
Minamitani H., Kawamura T., Sekizuka E., Shimizu T, Tsukada K. and Oshio C., Deformability and viscoelasticity of diabetic erythrocytes measured by microchannel flow system and atomic force microscope, 21st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 1999 (Atlanta).
Nagai, T., Sekizuka E., Tsukada K., Shimizu T., Minamitani H., Hokari, R., Oshio C., Effects of aldose reductase inhibitor in diabetic rats, 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 1998 (Hong Kong)
Tsukada K., Sekizuka E., Oshio C., Nagai T. and Minamitani H., Capillary model of crystal microchannel for red blood cell deformability measurement, 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 1997 (Chicago).
Tsukada K., Minamitani H., Sekizuka E. and Oshio C., Blood flow measurement system for microcirculation by image correlation method, 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 1996 (Amsterdam).